Introduction
Perhaps one of the drug medications that deserve to be given some praise is domperidone for being a medication that helps your digestive system to be free of obstacles and facilitate smooth movement through it. It may not have the same popularity as other drug medications, but it does what it’s expected to do in clearing up you system and prevent the development of nausea and vomiting as well as increasing the production of breast milk in women.
The typical usages of domperidone
Domperidone is mainly used for facilitating the smooth movement of substance through the digestive system by ensuring that there are no obstacles to prevent these movements.
The drug medication is also used to treat any symptoms of stomach upsets that set in which can cause irritability and discomfort to the victim.
The medication can also be put to use to prevent the onslaught of nausea and vomiting which are caused by some other drug medications and alleviate the discomforts associated with these symptoms.
It has not been recommended for use by women who breast feed to increase the amount of breast milk available for breastfeeding in women.
How is domperidone used?
You should use this drug medication by ingesting it through the mouth usually about 30 minutes before meals and when you go to bed.
You shouldn’t increase your dose or take your dose more often than as directed by your doctor.
If you do these irregular actions, you’ll find that your condition won’t improve any faster but your risk of suffering from side effects will increase.
The side effects domperidone can cause
Listed below are some of the side effects that can be caused from taking this drug medications
For the first several days of taking domperidone, you are sure to experience any of the following side effects such as headache, dry mouth, dizziness, nervousness, irritability, or flushing may take place as your body starts to tune in and adapt to the drug medication.
Side effects that have also been reported include: trouble sleeping (difficulty sleeping), stomach cramps, leg cramps, and hot flashes.
You should immediately inform your doctor if the symptoms become to be bothersome for your comfort.
You should also notify your doctor promptly if you happen to develop the following symptoms: chest pain, heart palpitations that involve slow/fast/irregular heartbeat, swelling of your feet or ankles, difficulty urinating, swelling of your breasts or a strange discharge from the nipple (men and women).
You may also experience menstrual discharge, and sexual performance problems. If you notice any other side effects not included in the above list, you should quickly contact your doctor or pharmacist.
Precautions you need to take
In order for you to guard against the adverse effects of domperidone related side effects, you should follow these instructions.
Inform your doctor about your medical history especially your medical history on breast cancer, or allergies. You should limit your consumption of alcoholic beverages.
You should also note that domperidone can only be used in women while they’re pregnant if there’s a clear need for using it. You should discuss the risks and benefits with your doctor.
It’s known that domperidone can pass into breast milk so because of the dangers that may befall the infant being nursed breastfeeding while taking this drug medication is not recommended.
Drug interactions
Due to the action of this drug medication of facilitating and enhancing movements in the digestive tract, it’s possible that it may affect the absorption and treatment potencies of other drug medications.
Because of this, it’s crucial that you inform you doctor about any prescription and nonprescription medication you are taking or may be taking.
This is especially important if you are taking or may take MAOI inhibitors such as, furazolidone,
phenelzine, selegiline, or tranylcypromine. Note also that you shouldn’t begin or halt your treatment without the approval of your doctor or pharmacist.
It’s essential to list down all other medications that can interact with domperidone so as to avoid possible interactions and complications.
You should also note that some of the drug medications listed below may be allowed to be used in combination with domperidone despite the fact that this may cause an interaction.
It will be entirely up to your professional practitioner or your pharmacist to advise on which combination can be allowed to take place and any precautionary steps that need to be taken.
Here is a list of the medications:
- alfuzosin
- amantadine
- amiodarone
- anticholinergics (e.g., benztropine, , oxybutinin)
- antihistamines (e.g., cetirizine, doxylamine, diphenhydramine, hydroxyzine, loratadine)
- antipsychotic medications (e.g., haloperidol, risperidone, quetiapine)
- apomorphine
- aprepitant
- “azole” antifungals (e.g., fluconazole, itraconazole, ketoconazole, voriconazole)
- buprenorphine
- buserelin
- capecitabine
- calcium channel blockers (e.g., amlodipine, diltiazem, nifedipine, verapamil)
- ceritinib
- chloral hydrate
- chloroquine
- cobicistat
- conivaptan
- crizotinib
- cyclosporine
- degarelix
- disopyramide
- donepezil
- doxepin
- dronedarone
- famotidine
- fingolimod
- flecainide
- formoterol
- galantamine
- grapefruit juice
- HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs; e.g., delavirdine, efavirenz, etravirine, nevirapine)
- HIV protease inhibitors (e.g., indinavir, atazanavir, lopinavir, nelfinavir, ritonavir)
- hydroxychloroquine
- indacaterol
- indapamide
- ivabradine
- lithium
- lomitapide
- loperamide
- macrolide antibiotics (e.g., azithromycin, clarithromycin, erythromycin)
- maprotiline
- mefloquine
- methadone
- metoclopramide
- metronidazole
- mifepristone
- mirabegron
- mirtazapine
- monoamine oxidase inhibitors (MAOIs; e.g., moclobemide, phenelzine, rasagiline, selegiline, tranylcypromine, nefazodone)
- octreotide
- olodaterol
- pentamidine
- primaquine
- probucol
- procainamide
- propafenone
- protein kinase inhibitors (e.g., bosutinib, dasatinib, erlotinib, imatinib, nilotinib)
- romidepsin
- quinidine
- quinine
- quinolone antibiotics (e.g., ciprofloxacin, moxifloxacin, norfloxacin, levofloxacin)
- salmeterol
- selective serotonin reuptake inhibitors (SSRIS; e.g., citalopram, fluoxetine, paroxetine, sertraline)
- serotonin antagonists (anti-emetic medications; e.g., granisetron, ondansetron)
- simeprevir
- solifenacin
- sotalol
- stiripentol
- sulfamethoxazole
- tacrolimus
- tamoxifen
- tetrabenazine
- trazodone
- tricyclic antidepressants (e.g., amitriptyline, nortriptyline)
- trimethoprim
- vardenafil
- venlafaxine
- vilanterol
- vorinostat
Overdosing on domperidone
If you suspect that you’ve overdosed on your medication, you should immediately make contact with the poison control center or emergency room in your area.
Symptoms that may result from overdosing can include: drowsiness, confusion or dizziness, irregular heartbeat, rigidity of your muscles, and twitching.
In the face of these symptoms, it’s quite likely that laboratory tests may be carried out periodically while you are taking this drug for the treatment of your condition.
This is carried out so that the effects of the treatment can be monitored and its side effects prevented.
Missing a dose
Missing your dose inadvertently has been known to happen and if it happens in your case, you should take the missed dose when you discover you have missed it.
However, you should not take the missed dose if you are about to take your normal dose very soon. You should instead skip the missed dose and take your normal dose.
You should never take two tablets at the same time and you should never double up to make up for a dose that you’ve missed.
Takeaway
It’s extremely important to seriously pay attention to the process of drug interaction where two drug medications come together in a combined usage. The danger of interaction is that it may have an undesired effect on the effectiveness of one of the drug medications by nullifying the effect it may have in treating a condition thereby rendering it incapable of effectively treating that condition. When this happens, successful treatment is negated and the risk of more side effects increases. You can purchase medicines, including Domperidone, from this reputable vendor; we have done so before.
